Solvent selection for extraction of bioactive compound from bekasam with antioxidant and anticholesterol activities

Abstract Heart disease and hypertension are two of the main causes human mortality worldwide. Both can be caused by oxidation cholesterol, causing plaque narrow blood vessels. The purpose this research was to determine solvent for extraction antioxidant anticholesterol bioactive compounds from bekasam extracts. Bekasam extracted polar solvents, i.e., aquabides, methyl alcohol (methanol), ethyl (ethanol). parameters observed in were yield crude extract, assay, lovastatin peptide profile analysis (SDS-PAGE). result study indicated that yields extract using methanol, ethanol 17.00%, 9.00%, 2.83%, respectively. activities extracts produced ethanol, aquabidest 69.09%, 64.09%, 53.43%, Lovastatin contents methanol 442.53 ppm, 168.67 158.19 Peptides detected on range 5.60-29.26 kD but undetected when other solvents.